The Science of Frailty

British Geriatrics Society

Dr. Roman Romero-Ortuno (@rrorthy7) is a newly appointed Consultant Geriatrician at Addenbrooke’s Hospital, Cambridge. In this blog, he outlines the scientific underpinnings of frailty and how this emerging science will lead to greater personalisation of treatments.shutterstock_117397708

Frailty is vulnerability to decompensation after a stressor event and is a consequence of cumulative decline in many physiological systems during a lifetime.

Campbell & Buchner defined frailty as ‘a condition or syndrome which results from a multi-system reduction in reserve capacity to the extent that a number of physiological systems are close to, or past, the threshold of symptomatic clinical failure; and as a consequence the frail person is at increased risk of disability and death from minor external stresses’.

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